1. Kakashi: Kakashi is a crucial figure in Konoha Village as the teacher of the three main characters. He is known for his super-level strength and high combat IQ. Despite being a versatile ninja proficient in ninjutsu, genjutsu, and taijutsu, his only drawback is having less chakra. As a close friend of Might Guy, Kakashi rarely uses the Eight Gates technique, as he can only open a maximum of four gates.
2. Second Hokage: The Second Hokage, likely the inventor of the Eight Gates technique, is known for his mastery of forbidden jutsu. Uchiha Madara's recognition of the technique implies its existence during his time. Therefore, the Second Hokage, as its developer, should also be able to use it.
3. Might Guy: Might Guy is an elite Jounin with strength surpassing the Five Kage, despite having poor memory.
4. Might Duy: Might Guy's father, a forever Genin, raised his son and taught him the Eight Gates technique. During the Third Ninja World War, Might Duy arrived in time to save Konoha's future and defeat the powerful Ninja Swordsmen of the Mist, potentially damaging Uchiha Madara.
5. Rock Lee: Although not proficient in ninjutsu, Rock Lee focuses on training his taijutsu skills due to his difficulty in using ninjutsu and condensing chakra. Inspired by Rock Lee's efforts, Might Guy taught him the Eight Gates technique. While in Naruto, Rock Lee only opens up to the Sixth Gate, it is possible that he could surpass his master in Boruto.