1. Uzumaki Mito: As the first Jinchuriki of the Nine-Tails and the wife of the first Hokage, Uzumaki Mito possessed great power. Being a member of the Uzumaki clan, her strength was comparable to Uchiha Madara's before he unlocked the Rinnegan.

2. Kaguya Otsutsuki: Kaguya is the origin of chakra in the ninja world and the entire ninja world was created to resurrect her. After her resurrection, she displayed her legendary powers, almost defeating Naruto and Sasuke.

3. Black Zetsu: Created by Kaguya, Black Zetsu ambushed and left Uchiha Madara powerless.

4. First Hokage: The First Hokage, possessing the power of the Sage of Six Paths and Wood Release, defeated Madara multiple times despite Madara's ability to control the Nine-Tails.

5. Might Guy: Despite limited chakra and weakness in ninjutsu, Might Guy's exceptional physical abilities made him feared by Madara. His activation of Eight Gates nearly defeated Six Paths, Madara, instilling a sense of dread.