1. Tobirama Senju: Despite his forbidden jutsu and unmatched speed, Tobirama was killed by the Gold and Silver Brothers. His sacrifice protected his disciples.
2. Minato Namikaze: One of the most talented ninjas, Minato died during the Nine-Tails attack. He sacrificed himself to protect Konoha and maintain the balance of power.
3. Hashirama Senju: After defeating Madara Uchiha, Hashirama's death was necessary to progress the plot of the First Shinobi World War.
4. Third Kazekage: The strongest Kazekage turned into a puppet by Sasori. Being controlled was a humiliation for the former leader.
5. Fourth Kazekage: Rasa, with his formidable abilities and role in the Sand Village's finances, was assassinated by Orochimaru. Their deaths were accidental and raised questions about the future of the Kazekage position in the Sand Village.