1. Uzumaki Kushina: Strong abilities, first Jinchuriki of Nine-Tails. The Nine-Tails transferred after her death. Possessed immense strength.

2. Uzumaki Kizuna: Naruto's mother, possibly from Uzumaki clan. Second Jinchuriki of Nine-Tails, skilled in sealing techniques. Sealed Nine-Tails' Tailed Beast Ball.

3. Uzumaki Karin: Part of Orochimaru's organization, infatuated with Sasuke. Pure Uzumaki bloodline, healing ability using blood.

4. Uzumaki Nagato (Pain): Chosen by Uchiha Madara, controlled Six Paths of Pain. Sacrificed himself using Outer Path: Samsara of Heavenly Life Technique to revive Leaf Village ninjas.

5. Uzumaki Naruto: Protagonist, third Jinchuriki of Nine-Tails. Inherited Uzumaki abilities, mastered its power.