1. Deidara vs Sasuke: After defeating Orochimaru, Sasuke targeted Akatsuki to find his brother, Itachi. Deidara, who was defeated by Itachi before, wanted to prove his art's superiority by taking down Sasuke. However, Sasuke's Raiton jutsu countered Deidara's explosive clay bombs. Sasuke escaped using his Spirit Transmigration jutsu, leaving Deidara drained of chakra.

2. Hidan: Learning the truth from Tobi, Sasuke agreed to join Akatsuki and attacked Konoha.

Sasuke's first mission was to capture the weaker Eight-Tails. But facing Killer Bee, things went wrong until his hawk squad intervened.

3. Raikage vs Sasuke: With Killer Bee captured, the Fourth Raikage called for a Five Kage Summit. Sasuke and Tobi surprise-attacked them, but the Raikage fought back, sacrificing his arm. Gaara saved Sasuke from the Raikage's final strike.

4. Danzo: Seeing Danzo as the mastermind behind his clan's massacre, Sasuke targeted him.

Despite multiple Sharingan eyes and an enhanced arm, Danzo narrowly escaped. Sasuke's genjutsu led to Danzo's demise, but Sasuke's eyes were severely damaged.

5. Madara vs Sasuke: Sasuke activated his Eternal Mangekyou Sharingan and joined Naruto to fight Tobi. They defeated him but faced resurrected Madara who took control of all Tailed Beasts. Madara saw Sasuke as arrogant and pierced his heart, but Karin saved Sasuke.