1. First Hokage: The "God of Shinobi" faced an assassination attempt by Kakuzu but remained unharmed. 

2. Fourth Mizukage: Yagura, a perfect jinchuriki, evaded multiple assassination attempts by Zabuza Momochi and caused his betrayal. 

3. Third Kazekage: Assassinated by Sasori, the "Strongest Kazekage" became a puppet, ending his powerful reign. 

4. Fourth Kazekage: Orochimaru's assassins killed the magnetic sand manipulator and covered his body in insects. 

5. Fifth Kazekage: Gaara, the Fifth Kazekage, defended himself against his father's assassination attempt and triggered his tailed beast transformation.